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Oct 7, - Absorption, distribution and excretion of MDI was studied in rats using a single dermal administration of (14)C-MDI dissolved in acetone at.

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Nov 28, - Skin exposure has also been implicated as a risk factor for isocyanate asthma in several epidemiologic studies of MDI-exposed workers, in which measured inhalation exposures were all very low or nondetectable. The authors concluded that skin could be an important route of exposure, leading to sensitization and asthma.‎Abstract · ‎Methods · ‎Results and Discussion · ‎Conclusion.

Jump to Animal Experiments and in vitro Studies - The main effects of MDI and PMDI are the effects on the In the various studies, the following parameters .. of absorption on respiratory sensitization caused by A comparative study with dermal ( µl and 75 µl) . Unlike with TDI, with MDI dissolved in ethylene ‎Abstract · ‎Mechanism of Action · ‎Toxicokinetics and · ‎Effects in Humans.

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